Development of high-resolution and high-sensitivity brain PET insert for 7 T MRI scanner

First results from a high-resolution small animal PET insert for PET/MRI imaging

University of Manitoba, Canada We have recently completed construction of a high resolution small animal PET insert designed for operation inside a Bruker 7T MRI. The PET insert is designed to achieve a 1 mm spatial resolution in the centre of its field of view (FOV) and fit within the 114 mm inner diameter of the Bruker BGA-12S gradient coil while accommodating the Bruker 35 mm volume RF coil ...

Design of a very high-resolution small animal PET scanner using a silicon scatter detector insert.

A small animal positron emission tomography (PET) instrument using a high-resolution solid-state detector insert in a conventional PET system was investigated for its potential to achieve sub-millimeter spatial resolution for mouse imaging. Monte Carlo simulations were used to estimate the effect of detector configurations (thickness, length and radius) on sensitivity. From this initial study, ...

Implantable Microsystems for High-Resolution Interfacing to the Brain

Development of a high-resolution detection module for the INSERT SPECT/MRI system

Politecnico di Milano, Dipartimento di Elettronica, Informazione e Bioingegneria, Via Golgi 40, 20133 Milano, Italy A new multi-modality imaging tool is under development in the framework of the INSERT (Integrated SPECT/MRI for Enhanced Stratification in Radio-chemo Therapy) project, supported by the European Community. The final goal is to develop a custom SPECT apparatus that can be used as a...

Cortical thickness determination of the human brain using high resolution 3 T and 7 T MRI data

PURPOSE The analysis of the human cerebral cortex and the measurement of its thickness based on MRI data can provide insight into normal brain development and neurodegenerative disorders. Accurate and reproducible results of the cortical thickness measurement are desired for sensitive detection. This study compares ultra-high resolution data acquired at 7T with 3T data for determination of the ...